We employ the QCD sum rules method for
description of nucleons in nuclear matter. We
show that this approach provides a consistent
formalism for solving various problems of
nuclear physics. Such nucleon characteristics as
the Dirac effective mass $m^*$ and the vector
self-energy $\Sigma_V$ are expressed in terms of
the in-medium values of QCD condensates. The
values of these parameters at saturation density
and the dependence on the baryon density and on
the neutron-to-proton density ratio is in
agreement with the results, obtained by
conventional nuclear physics method. The
contributions to $m^*$ and $\Sigma_V$ are
related to observables and do not require
phenomenological parameters. The scalar
interaction is shown to be determined by the
pion-nucleon $\sigma$-term. The nonlinear
behavior of the scalar condensate may appear to
provide a possible mechanism of the saturation.